Also Known as Brintellix
Top brand choice
Strength | Pack Size | Qty | |
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Strength
5mg
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Strength
10mg
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Strength
15mg
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Strength
20mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Trintellix is a medication primarily used to treat major depressive disorder (MDD) in adults. It belongs to the class of drugs known as serotonin modulators and stimulators (SMS), which work by enhancing the activity of serotonin, a neurotransmitter involved in mood regulation.
Unlike some antidepressants that primarily inhibit serotonin reuptake, Trintellix works via multiple mechanisms of action, including serotonin reuptake inhibition, receptor activity modulation, and neurotransmitter release enhancement, which may contribute to its efficacy in treating depression.
Fact Table | |
Formula |
C18H22N2S |
License |
US DailyMed, EU EMA, US FDA |
Bioavailability |
75% |
Legal status |
Rx-Only |
Chemical Name |
Vortioxetine |
Elimination half-life |
66 hours |
Dosage (Strength) |
5mg, 10mg, 15mg, 20mg |
Pregnancy |
Not recommended |
Brands |
Trintellix |
Protein binding |
98–99% |
PubChem CID |
9966051 |
MedlinePlus |
a614003 |
ChEBI |
76016 |
ATC code |
N06AX26 |
DrugBank |
DB09068 |
KEGG |
D10184 |
Routes of administration |
By mouth |
The usual dosage of Trintellix is 5-20 mg by mouth once daily with or without food.
The active ingredient in Trintellix is vortioxetine.
Common drug-drug interactions may include:
Use Trintellix with caution if you have a history of suicidal thoughts or behaviors, bipolar disorder, seizures, or liver impairment.
It may increase the risk of suicidal thinking and behavior, particularly in young adults.
Regular monitoring for worsening depression or emergence of suicidal thoughts is recommended during treatment with Trintellix.
Common adverse reactions to Trintellix may include:
What is Trintellix used for?
Trintellix is a prescription medication for treating major depressive disorder (MDD) in adults. It helps rebalance brain chemicals.
Why is Trintellix so expensive?
Trintellix's high cost reflects the extensive research and testing required to ensure its safety and effectiveness as a brand-name medication.
Does Trintellix cause weight gain?
While clinical trials didn't show significant weight changes, some users have reported weight gain after starting Trintellix.
Can you take more than 20 mg of Trintellix?
No, the safety and effectiveness of doses above 20 mg/day haven't been studied in controlled trials. The maximum dosage for treating depression is 20 mg/day.
How long does Trintellix take to work?
Most people notice some improvement after two weeks, but it may take four weeks or longer to experience the full benefits of Trintellix.
Is Trintellix a controlled substance?
No, Trintellix isn't classified as a controlled substance.
Can Trintellix help anxiety?
While not FDA-approved for anxiety, Trintellix has been used off-label for severe cases of generalized anxiety disorder (GAD).
What are the side effects of Trintellix?
Trintellix can cause a range of side effects, including nausea (the most common), as well as itching, weight gain, gastrointestinal issues, headaches, and more serious effects like serotonin syndrome or allergic reactions.
What exactly does Trintellix do?
Trintellix is believed to work as an antidepressant by increasing serotonin activity in the brain, primarily by blocking its reuptake.
What is the most common side effect of Trintellix?
Nausea is the most reported side effect of Trintellix use.