Voquezna (Vonoprazan)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
10mg
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Strength
20mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Voquezna is a prescription medication primarily used for the treatment of acid-related gastrointestinal disorders such as gastroesophageal reflux disease (GERD) and peptic ulcers.

It belongs to a class of drugs known as potassium-competitive acid blockers (P-CABs). These drugs work by inhibiting acid production in the stomach, providing relief from symptoms like heartburn, acid reflux, and stomach ulcers.

Fact Table

Formula

C17H15FN4O2

License

US FDA

Bioavailability

Approximately 51%

Legal status

Prescription only

Chemical Name

(R)-1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine

Elimination half-life

7.7 hours

Dosage (Strength)

10 mg, 20 mg tablets

Pregnancy

Consult a doctor

Brands

Voquezna, Takecab, P-CAB

Protein binding

80-85%

PubChem CID

9871428

MedlinePlus

a622006

ChEBI

CHEBI:134722

ATC code

A02BD14

DrugBank

DB12254

KEGG

D09761

Routes of administration

Oral

Directions

The usual dosage is 10-20 mg by mouth once daily.

The duration of treatment depends on what condition Voquezna is prescribed for.

Take with or without food. Do not chew, crush, or break tablets.

Ingredients

The active ingredient in Voquezna is vonoprazan.

Interactions

Common drug-drug interactions may include:

  • Abemaciclib
  • Acalabrutinib
  • Alfentanil
  • Amiloride
  • Apalutamide
  • Astemizole
  • Atazanavir
  • Avacopan
  • Axitinib
  • Bedaquiline
  • Bemetizide
  • Bendroflumethiazide
  • Benzhydrocodone
  • Benzthiazide
  • Bosentan
  • Bosutinib
  • Brigatinib
  • Budesonide
  • Bumetanide
  • Canrenoate
  • Canrenone
  • Carbamazepine
  • Cenobamate
  • Ceritinib
  • Chlorothiazide
  • Chlorthalidone
  • Cilostazol
  • Cisapride
  • Citalopram
  • Clindamycin
  • Clopamide
  • Clopidogrel
  • Cobimetinib
  • Codeine
  • Colchicine
  • Conivaptan
  • Crizotinib
  • Cyclopenthiazide
  • Cyclosporine
  • Cyclothiazide
  • Dabrafenib
  • Dasatinib
  • Diazoxide
  • Digoxin
  • Dihydrocodeine
  • Dihydroergotamine
  • Dipyrone
  • Docetaxel
  • Dofetilide
  • Dronedarone
  • Efavirenz
  • Elagolix
  • Entrectinib
  • Enzalutamide
  • Eplerenone
  • Ergotamine
  • Ethacrynic Acid
  • Etozolin
  • Etravirine
  • Everolimus
  • Fentanyl
  • Flibanserin
  • Fosphenytoin
  • Furosemide
  • Hydrochlorothiazide
  • Hydrocodone
  • Hydroflumethiazide
  • Indapamide
  • Ivosidenib
  • Levomethadyl
  • Lomitapide
  • Lorlatinib
  • Lumacaftor
  • Mavacamten
  • Meperidine
  • Methadone
  • Methyclothiazide
  • Metolazone
  • Midostaurin
  • Mitotane
  • Modafinil
  • Nafcillin
  • Nelfinavir
  • Neratinib
  • Nilotinib
  • Olaparib
  • Oxycodone
  • Paclitaxel
  • Pazopanib
  • Phenobarbital
  • Phenytoin
  • Pimavanserin
  • Pimozide
  • Piretanide
  • Polythiazide
  • Primidone
  • Quinethazone
  • Quinidine
  • Quinine
  • Ribociclib
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Roflumilast
  • Ruxolitinib
  • Sirolimus
  • Sonidegib
  • Spironolactone
  • St John's Wort
  • Sufentanil
  • Sunitinib
  • Tacrolimus
  • Tamoxifen
  • Telotristat Ethyl
  • Temsirolimus
  • Thioridazine
  • Tolvaptan
  • Torsemide
  • Tramadol
  • Triamterene
  • Trichlormethiazide
  • Warfarin
  • Xipamide
  • Zanubrutinib

Cautions

Before starting Voquezna, inform your doctor if you have any history of liver problems, osteoporosis, or low magnesium levels.

Do not take Voquezna if you are allergic to vonoprazan or any other components of the medication.

Side Effects

The most common side effects of this drug can include:

  • Abdominal distension symptom
  • Abdominal pain
  • Anaphylaxis
  • Candidiasis, Vulvovaginal
  • Constipation
  • Diarrhea
  • Gastritis
  • Headache
  • Hypertension
  • Indigestion
  • Liver failure
  • Nausea
  • Nasopharyngitis
  • Respiratory
  • Stevens-Johnson syndrome
  • Taste sense altered
  • Toxic epidermal necrolysis
  • Tubulointerstitial nephritis, acute
  • Urinary tract infectious disease

References

Voquezna [package insert]. Buffalo Grove, IL: Phathom; 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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