Top brand choice
Strength | Pack Size | Qty | |
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Strength
400/100/100mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) is prescription medication used for treating adults with chronic hepatitis C virus (HCV) infection.
Vosevi comes in tablets that contain 400 mg sofosbuvir, 100 mg velpatasvir, and 100 mg voxilaprevir. Vosevi is administered orally.
Fact Table | |
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Formula | Sofosbuvir: C22H29FN3O9P Velpatasvir: C49H54N8O8 Voxilaprevir: C40H52F4N6O9S |
License | FDA approved |
Bioavailability | Sofosbuvir: Approximately 80% Velpatasvir: Not specified; enhanced with food Voxilaprevir: Not specified; enhanced with food |
Legal status | Prescription only |
Chemical Name | Sofosbuvir/Velpatasvir/Voxilaprevir |
Elimination half-life | Sofosbuvir: Approximately 0.4 hours Velpatasvir: Approximately 15 hours Voxilaprevir: Approximately 33 hours |
Dosage (Strength) | 400 mg Sofosbuvir / 100 mg Velpatasvir / 100 mg Voxilaprevir per tablet |
Pregnancy | Consult a healthcare provider; data on use in pregnancy is limited |
Brands | Vosevi |
Protein binding | Sofosbuvir: 61-65% Velpatasvir: >99% Voxilaprevir: >99% |
PubChem CID | Sofosbuvir: 45375808 Velpatasvir: 67683367 Voxilaprevir: 71799753 |
MedlinePlus | a617031 |
ChEBI | Sofosbuvir: 85083 Velpatasvir: 133022 Voxilaprevir: 134025 |
ATC code | J05AX65 |
DrugBank | Sofosbuvir: DB08934 Velpatasvir: DB11613 Voxilaprevir: DB12036 |
KEGG | Sofosbuvir: D10366 Velpatasvir: D10861 Voxilaprevir: D10862 |
Routes of administration | Oral |
Vosevi should be taken as directed by your doctor, who will determine an appropriate treatment regimen for you.
Recommended dosing:
Store Vosevi tablets in the original container below 30°C (86°F); keep away from children.
For further instructions for use, carefully read the information leaflet that accompanies your Vosevi prescription.
Contact your doctor or pharmacist if you have any questions or concerns.
Sofosbuvir, velpatasvir, and voxilaprevir are the active ingredients in Vosevi.
Colloidal silicon dioxide, copovidone, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose are the inactive ingredients included. Ferrosoferric oxide, iron oxide red, iron oxide yellow, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide are contained in the tablet film coat.
Vosevi should not be taken with rifampin.
Vosevi side effects include but are not limited to headache, fatigue, diarrhea, and nausea. Contact your doctor right away if you have side effects that are bothersome or persistent.
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