Vraylar (Cariprazine)

Also Known as Reagila

Prescription medicineOnly Available By Prescription
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Top brand choice

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Strength
1.5mg
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3mg
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4.5mg
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Strength
6mg
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Top Generic choice

Strength Pack Size Qty
Strength
1.5mg
Pack Size
Qty
Strength
3mg
Pack Size
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Strength
4.5mg
Pack Size
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Strength
6mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Vraylar is a prescription medication that can treat bipolar disorder and schizophrenia. 

Vraylar works by increasing the amount of dopamine activity in the brain. It is not well understood how Vraylar works for mental health conditions.

Fact Table

Formula

C21H32Cl2N4O

License

US FDA

Bioavailability

High

Legal status

Rx-only

Chemical Name

Cariprazine

Elimination half-life

2–5 days

Dosage (Strength)

1.5mg, 3mg, 4.5mg, 6mg

Pregnancy

Consult Doctor

Brands

Vraylar, Reagila

Protein binding

91–97%

PubChem CID

11154555

MedlinePlus

a615050

ChEBI

90933

ATC code

N05AX15

DrugBank

DB06016

KEGG

D09997

Routes of administration

By mouth

Directions

Take Vraylar exactly as prescribed by your healthcare provider. 

The starting dose of Vraylar is 1.5 mg once daily. The dose may be increased to 3-4.5 mg once daily.

Ingredients

The main ingredient in Vraylar is cariprazine.

Interactions

Vraylar has the potential of many drug-drug interactions. Tell your doctor and pharmacist about all of the drug you are taking, including: 

  • Amiodarone
  • Apalutamide
  • Aprepitant
  • Atazanavir
  • Berotralstat
  • Bexarotene
  • Bosentan
  • Carbamazepine
  • Cenobamate
  • Ceritinib
  • Cimetidine
  • Clarithromycin
  • Conivaptan
  • Crizotinib
  • Cyclosporine
  • Dabrafenib
  • Darunavir
  • Dexamethasone
  • Diltiazem
  • Dipyrone
  • Dronedarone
  • Duvelisib
  • Efavirenz
  • Enzalutamide
  • Erythromycin
  • Eslicarbazepine
  • Etravirine
  • Fedratinib
  • Fluconazole
  • Fosamprenavir
  • Fosaprepitant
  • Fosphenytoin
  • Grapefruit juice
  • Idelalisib
  • Imatinib
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lefamulin
  • Letermovir
  • Lonafarnib
  • Lopinavir
  • Lorlatinib
  • Lumacaftor
  • Lumacaftor-ivacaftor
  • Mifepristone
  • Mitotane
  • Modafinil
  • Nafcillin
  • Nefazodone
  • Nelfinavir
  • Netupitant
  • Nilotinib
  • Pexidartinib
  • Phenobarbital
  • Phenytoin
  • Posaconazole
  • Primidone
  • Ribociclib
  • Rifabutin
  • Rifampin (rifampicin)
  • Rifapentine
  • Saquinavir
  • Schisandra
  • St. John's wort
  • Telithromycin
  • Tucatinib
  • Verapamil
  • Voriconazole

Cautions

Tell your doctor if you have an increase in suicidal thoughts and behaviors while taking Vraylar.

Vraylar should not be used by older adults to treat dementia-related psychosis.

Tell your healthcare provider if you have a history of kidney or liver problems.

Ask your pharmacist or doctor for a full list of precautions.

Side Effects

The most common side effects from Vraylar can include:

  • Abdominal pain
  • Akathisia
  • Anxiety
  • Arthralgia
  • Suicidal ideation
  • Back pain
  • Blurred vision
  • Constipation
  • Decreased appetite
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dyspepsia
  • Dystonia
  • Extrapyramidal reactions
  • Fatigue
  • Headache
  • Hypertension
  • Increased creatinine phosphokinase
  • Increased liver enzymes
  • Insomnia
  • Agitation
  • Limb pain
  • Muscle rigidity
  • Nausea
  • Parkinsonian-like syndrome
  • Restlessness
  • tachycardia
  • Toothache
  • Vomiting
  • Weight gain
  • Xerostomia

References


Vraylar [package insert]. Parsippany, NJ: Actavis; 2015.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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