Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
231mg
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Vumerity is an oral prescription medication used primarily in the treatment of relapsing forms of multiple sclerosis (MS) in adults. MS is a chronic, often disabling neurological condition where the immune system attacks the protective covering of nerves, leading to a range of symptoms, including physical, cognitive, and emotional issues. Relapsing forms of MS are characterized by periods of worsening symptoms followed by partial or complete recovery.
Vumerity works by modulating the immune system, helping to reduce the frequency of these relapses, slow the progression of physical disability, and mitigate inflammation that could cause further nerve damage.
The active ingredient, diroximel fumarate, is believed to activate the Nrf2 pathway. This pathway helps protect nerve cells from oxidative stress and reduces inflammation, potentially preserving nerve function over time.
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Fact Table |
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Formula |
C14H18N2O8 |
|
License |
US FDA |
|
Bioavailability |
Not applicable (Prodrug, rapidly converted to monomethyl fumarate) |
|
Legal status |
Prescription only |
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Chemical Name |
2-[(S)-2-[(3,5-Dioxo-4-oxazolidinyl)methoxy]ethyl] fumarate |
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Elimination half-life |
1 hour (as monomethyl fumarate) |
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Dosage (Strength) |
231 mg delayed-release capsules |
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Pregnancy |
Consult a doctor |
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Brands |
Vumerity |
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Protein binding |
27-40% (as monomethyl fumarate) |
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PubChem CID |
11555836 |
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MedlinePlus |
a619034 |
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ChEBI |
CHEBI:145277 |
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ATC code |
N07XX14 |
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DrugBank |
DB15188 |
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KEGG |
D11091 |
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Routes of administration |
Oral |
The recommended dose is 231 mg twice daily for the first seven days, followed by 462 mg twice daily.
You can take Vumerity with or without food, but avoid taking it with high-fat meals, as this may reduce its absorption.
Take Vumerity capsules whole. Do not crush, chew, or break them.
The active ingredient in Vumerity diroximel fumarate.
There are only a few known serious drug-drug interactions with Vumerity, which are:
Before starting Vumerity, inform your healthcare provider if you have a history of liver problems, kidney issues, or low white blood cell counts.
Tell your doctor if you have a history of limb swelling (angioedema).
Women who are pregnant or breastfeeding should discuss potential risks with their doctor, as the safety of Vumerity during pregnancy and breastfeeding is not fully established.
Avoid taking Vumerity if you are allergic to diroximel fumarate or any of its components.
Avoid taking any live vaccines while on Vumerity treatment.
Common side effects of this drug may include:
Vumerity [package insert]. Cambridge, MA: Biogen; 2024.
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
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