April 18, 2025 by Mary F. (NH, United States)
“Thank goodness for Canada Drugs Direct! I'm able to save money on my prescription for Mounjaro. It's still not inexpensive but it's a much better price than in the USA.”
Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
0.024%/5ml
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Pack Size
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Qty
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
VYZULTA eye drops are a medication used to treat increased intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma. Increased fluid pressure inside the eye occurs when more fluid is produced than is drained.
Ocular hypertension is a primary risk factor for glaucoma. Left untreated, glaucoma can lead to visual impairment and permanent optic nerve damage.
VYZULTA eye drops work by a dual mechanism. It is metabolized into two active moieties at the site of action: latanoprost and butanediol mononitrate. Latanoprost works by increasing the expression of proteins that degrade collagen, thereby reducing outflow resistance and producing subsequent pressure reduction. Butanediol mononitrate further metabolizes to nitric oxide, which causes changes in contractility and reduced aqueous humor volume.
| Fact Table | |
| Formula |
C27H41NO8 |
| License |
US DailyMed |
| Bioavailability |
- |
| Legal status |
Rx-Only |
| Chemical Name |
Latanoprostene bunod |
| Elimination half-life |
1.8–4.6 hours |
| Dosage (Strength) |
0.024%/5ml |
| Pregnancy |
Not Recommended |
| Brands |
Vyzulta |
| Protein binding |
- |
| PubChem CID |
11156438 |
| MedlinePlus |
a618001 |
| ChEBI |
177703 |
| ATC code |
S01EE06 |
| DrugBank |
DB11660 |
| KEGG |
D10441 |
| Routes of admsinistration |
Eye drop |
Instill one drop into the conjunctival sac of the affected eyes (s) once daily in the evening. VYZULTA eye drops should not be administered more than once daily as the subsequent effects may diminish.
Separate the administration from other eye drops by at least 5 minutes. Wait 15 minutes after administration of drops to insert contact lenses.
Do not touch the tip of the eyedropper to the surface of the eye or other nonsterile surfaces, as this may contaminate the bottle with bacterial growth.
The active ingredient in VYZULTA eye drops is latanoprostene bunod.
Inactive ingredients include: benzalkonium chloride (preservative), citric acid, EDTA, glycerin, polysorbate 80, sodium citrate, and water.
VYZULTA eye drops can cause permanent pigmentation changes to the iris, and reversible pigmentation changes to the periorbital tissue and eyelashes. Pigmentation changes include a darkening of the affected tissue. Patients prescribed VYZULTA eye drops should be informed of this possibility by their prescribing physician.
VYZULTA eye drops can increase the length and thickness of eyelashes. These changes are cosmetic and usually reversible upon discontinuation.
The most common adverse effects of VYZULTA eye drops include:
If you experience any of the above side effects while taking VYZULTA eye drops, let your doctor know. Most side effects will resolve after discontinuing the medication.
References
What is Vyzulta used for?
Vyzulta is used to lower eye pressure in people with open-angle glaucoma or ocular hypertension.
What are the side effects of Vyzulta?
Common side effects of Vyzulta include puffy eyelids, mild pain, blurred vision, and feeling like something's in your eye. Less common ones include eye irritation and swelling. Rare side effects include changes in vision, eye pain, and sensitivity to light. Serious side effects may include severe discomfort, redness, sudden vision changes, or severe pain, which require medical attention.
Why is Vyzulta so expensive?
Vyzulta's cost can vary due to factors like research, production, marketing, and distribution.
Is Vyzulta a beta blocker?
No, Vyzulta is not a beta blocker. It works differently by targeting two pathways to reduce eye pressure.
Does Vyzulta need to be refrigerated?
No, Vyzulta should be stored at room temperature, between 15°C and 25°C (59°F and 77°F). Avoid freezing or refrigerating it.
How much does Vyzulta lower eye pressure?
Vyzulta helps lower eye pressure by about 7.5 to 9.1 mmHg on average in studies, for people with an initial eye pressure of around 26.7 mmHg.
Is Vyzulta the same as latanoprost?
Vyzulta contains a modified form of latanoprost called latanoprostene bunod. Both lower eye pressure, but Vyzulta has a dual mechanism of action.
How long can you use Vyzulta?
The duration of Vyzulta use varies depending on your condition and your doctor’s advice. Regular check-ups with an eye specialist are important.
Who should not use Vyzulta?
Vyzulta should not be used by people allergic to it, as it can cause serious reactions. Those with certain eye issues, like swelling, infections, or past surgeries, should inform their doctor. It's not clear if it's safe during pregnancy or breastfeeding, so consult a doctor if you're in that situation. It's not suitable for anyone under 16. Also, it might gradually change eye color or eyelids and lashes, usually making them more brown, and this change could persist even after stopping treatment.
Product Reviews
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If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
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Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
