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| Strength | Pack Size | Qty | |
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Strength
4mg/5ml
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zometa (zoledronic acid) is an intravenous (IV) medication that is administered via an infusion for the treatment of high blood calcium levels due to malignancy and for the treatment of multiple myeloma and bone cancer from solid tumors.
| Fact Table | |
|---|---|
| Formula | C5H10N2O7P2 |
| License | FDA approved |
| Bioavailability | Not applicable (intravenous administration) |
| Legal status | Prescription only |
| Chemical Name | (1-hydroxy-2-imidazol-1-yl-phosphonoethyl)phosphonic acid |
| Elimination half-life | Biphasic: 1.87 hours (initial), up to 146 hours (terminal) |
| Dosage (Strength) | 4 mg/5 mL concentrate for solution, 4 mg/100 mL solution |
| Pregnancy | Not recommended; consult a healthcare provider |
| Brands | Zometa, Aclasta |
| Protein binding | Low (22% bound to plasma proteins) |
| PubChem CID | 68740 |
| MedlinePlus | a605023 |
| ChEBI | 10143 |
| ATC code | M05BA08 |
| DrugBank | DB00399 |
| KEGG | D01762 |
| Routes of administration | Intravenous |
Your healthcare provider will decide a treatment plan for you. A healthcare professional will administer Zometa via an IV infusion.
Inform your healthcare provider of any questions or concerns you have.
Zoledronic acid is the active ingredient in Zometa. Mannitol, USP, as bulking agent, water for injection, and sodium citrate, USP, as buffering agent, are the inactive ingredients.
Zometa drugs should not be administered to patients who have an allergy to any of its ingredients.
Zometa side effects include but are not limited to nausea, fatigue, anemia, bone pain, constipation, fever, vomiting, and shortness of breath. Inform your healthcare provider right away if you experience bothersome or persistent side effects.
Talk to your healthcare provider about Zometa.
Zometa. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2018.
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