Only Available By Prescription
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| Strength | Pack Size | Qty | |
|---|---|---|---|
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Strength
0.3% Foam Can
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Strength
0.3% Cream Tube
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zoryve (roflumilast) cream is prescribed to treat patients who are 6 years old or older with plaque psoriasis. It is for topical use.
Zoryve comes in 60-gram tubes that contain 3 mg of roflumilast per gram.
| Fact Table | |
|---|---|
| Formula | C17H14Cl2F2N2O3 |
| License | FDA approved |
| Bioavailability | Approximately 80% |
| Legal status | Prescription only |
| Chemical Name | 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide |
| Elimination half-life | Approximately 17 hours (for Roflumilast) and 30 hours (for the active metabolite, Roflumilast N-oxide) |
| Dosage (Strength) | 0.3% topical cream |
| Pregnancy | Consult a healthcare provider; limited data available |
| Brands | Zoryve |
| Protein binding | 99% |
| PubChem CID | 449190 |
| MedlinePlus | a611027 |
| ChEBI | 71102 |
| ATC code | D11AH07 |
| DrugBank | DB01656 |
| KEGG | D01208 |
| Routes of administration | Topical |
Zoryve should be used as your or your child’s doctor prescribes. It is recommended to apply the cream to the affected areas of the skin once daily.
Avoid contact with the mouth, eyes, or vaginal areas.
Zoryve cream should be kept between 20°C and 25°C (68°F and 77°F); keep out of reach of children.
There is a medication guide that comes with the prescription that can be referred to for more instructions on administration.
Speak to your or your child’s doctor or pharmacist if you have any questions or concerns.
Roflumilast is the active ingredient in Zoryve.
Inactive ingredients include the following: ceteareth-10 phosphate, cetearyl phosphate, cetostearyl alcohol, diethylene glycol monoethyl ether, hexylene glycol, isopropyl palmitate, methylparaben, propylparaben, purified water, sodium hydroxide, and white petrolatum. Hydrochloric acid may be added to balance the pH.
Zoryve cream is contraindicated in patients with moderate to severe liver impairment.
Some, but not all, Zoryve cream side effects include diarrhea, headache, sleeping issues, pain at the application site, upper respiratory tract infections, and urinary tract infections.
If you or your child experience bothersome or persistent side effects, immediately talk to a doctor.
Here, you can buy Zoryve cream!
Zoryve cream. Westlake Village, CA: Arcutis Biotherapeutics, Inc.; 2024.
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