Top brand choice
Strength | Pack Size | Qty | |
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Strength
150mg
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Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zykadia (ceritinib) is a prescription medication for treating non-small cell lung cancer that has spread to other parts of the body in adults.
Zykadia comes in 150 mg capsules and tablets for oral administration.
Fact Table | |
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Formula | C28H36ClN5O3S |
License | FDA approved |
Bioavailability | Approximately 58% (fed state) |
Legal status | Prescription only |
Chemical Name | 5-Chloro-2-[2-methoxy-4-(piperidin-4-yl)carbamoylphenylamino]-N-(5-methylsulfanyl-1H-pyrazol-3-yl)pyridine-3-carboxamide |
Elimination half-life | Approximately 41 hours |
Dosage (Strength) | 150 mg capsules |
Pregnancy | Not recommended; consult a healthcare provider |
Brands | Zykadia |
Protein binding | 97% |
PubChem CID | 57379381 |
MedlinePlus | a614048 |
ChEBI | 85081 |
ATC code | L01XE28 |
DrugBank | DB09055 |
KEGG | D09925 |
Routes of administration | Oral |
Zykadia should be taken as your healthcare provider has instructed. For product use information, refer to the medication guide that accompanies your prescription. Do not hesitate to reach out to your healthcare provider or pharmacist about any questions or concerns you may have.
The recommended Zykadia dosing is to take 450 mg by mouth one time a day with food.
Store Zykadia at room temperature between 68°F to 77°F (20°C to 25°C) and away from children’s reach.
Ceritinib is the active ingredient in Zykadia.
Colloidal silicon dioxide, hard gelatin capsule shells, low substituted hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, FD&C Blue # 2, gelatin, and titanium dioxide are the inactive ingredients in the 150 mg capsules.
Colloidal silicon dioxide, croscarmellose sodium, low-substituted hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, povidone, FD&C Blue # 2 aluminum lake, hypromellose, polyethylene glycol 4000, talc, and titanium dioxide are the inactive ingredients in the 150 mg tablets.
According to the most recent Prescribing Information, there are no contraindications to Zykadia.
Zykadia side effects include but are not limited to diarrhea, nausea, abdominal pain, vomiting, fatigue, decreased appetite, and weight loss. Contact your healthcare provider right away if you experience bothersome or persistent side effects.
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Zykadia. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2021.